생명공학대학 - 융합생명공학과

  • 교수 분자면역학
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관심분야

Study of functional role of cell cytoskeleton in inflammatory and tumorgenic responses 
Understanding of signal transduction pathway in inflammatory signaling 
Development of anti-inflammatory and anti-cancer drugs 
Functional role of protein methylation in immune responses

학력

  • (Ph.D.) 영국 University College London 면역학과

약력/경력

  • 2011.03.01 - 현재 : 성균관대학교 부교수(정년보장), 교수
  • 2015.01.01 - 현재 : 대한약학회 총무분과 위원
  • 2015.01.01 - 현재 : Journal of Ginseng Research Editor-in-Chief
  • 2003.03.02 - 2011.02.28 : 강원대학교 전임강사, 조교수, 부교수(정년보장)
  • 2003.03.02 - 2005.02.28 : 강원대학교 전임강사
  • 2001.11.08 - 2003.02.15 : 워싱턴대학교 의과대학 하워드휴즈 의학연구소,
  • Research Associate, 병리학과 Post-doc.
  • 1993.03.02 - 1998.06.15 : 대웅제약 중앙연구소 연구원, 선임연구원

학술지 논문

  • (2023)  Tumor-suppressive functions of protein lysine methyltransferases.  EXPERIMENTAL AND MOLECULAR MEDICINE.  55,  12
  • (2023)  Role of histone methylation in skin cancers: Histone methylation-modifying enzymes as a new class of targets for skin cancer treatment.  BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER.  1878,  3
  • (2022)  Callerya atropurpurea suppresses inflammation in vitro and ameliorates gastric injury as well as septic shock in vivo via TLR4/MyD88-dependent cascade.  PHYTOMEDICINE.  105,  -
  • (2022)  The EEF1AKMT3/MAP2K7/TP53 axis suppresses tumor invasiveness and metastasis in gastric cancer.  CANCER LETTERS.  544,  -
  • (2021)  Syk-MyD88 Axis Is a Critical Determinant of Inflammatory-Response in Activated Macrophages.  FRONTIERS IN IMMUNOLOGY.  12,  767366
  • (2021)  Cocculus hirsutus ameliorates gastric and lung injuries by suppressing Src/Syk.  PHYTOMEDICINE.  93,  153778
  • (2021)  Matricaria chamomilla (Chamomile) Ameliorates Muscle Atrophy in Mice by Targeting Protein Catalytic Pathways, Myogenesis, and Mitochondrial Dysfunction.  AMERICAN JOURNAL OF CHINESE MEDICINE.  49,  06
  • (2021)  Protective Effects of Maclurin against Benzo[a]pyrene via Aryl Hydrocarbon Receptor and Nuclear Factor Erythroid 2-Related Factor 2 Targeting.  ANTIOXIDANTS.  10,  8
  • (2021)  TAK1 in the AP-1 pathway is a critical target of Saururus chinensis (Lour.) Baill in its anti-inflammatory action.  JOURNAL OF ETHNOPHARMACOLOGY.  279,  114400
  • (2021)  Antimelanogenesis Effects of Theasinensin A.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  22,  14
  • (2021)  The regulatory role of Korean ginseng in skin cells.  JOURNAL OF GINSENG RESEARCH.  45,  3
  • (2021)  Dipterocarpus tuberculatus Roxb. Ethanol Extract Has Anti-Inflammatory and Hepatoprotective Effects In Vitro and In Vivo by Targeting the IRAK1/AP-1 Pathway.  MOLECULES.  26,  9
  • (2021)  In vivo anti-inflammatory effects of Prasiola japonica ethanol extract.  JOURNAL OF FUNCTIONAL FOODS.  80,  104440
  • (2021)  Antioxidative and Skin Protective Effects of Canarium subulatum Methanol Extract on Keratinocytes.  EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE.  2021,  6692838
  • (2021)  Pharmacological potential of ginseng and its major component ginsenosides.  JOURNAL OF GINSENG RESEARCH.  45,  2
  • (2021)  Enhancement of skin barrier and hydration-related molecules by protopanaxatriol in human keratinocytes.  JOURNAL OF GINSENG RESEARCH.  45,  2
  • (2021)  Olea europaea Suppresses Inflammation by Targeting TAK1-Mediated MAP Kinase Activation.  MOLECULES.  26,  6
  • (2021)  Mechanisms of Resorcinol Antagonism of Benzo[a]pyrene-Induced Damage to Human Keratinocytes.  BIOMOLECULES THERAPEUTICS.  29,  2
  • (2021)  DNA or Protein Methylation-Dependent Regulation of Activator Protein-1 Function.  CELLS.  10,  2
  • (2021)  Tunisian Olea europaea L. leaf extract suppresses Freund's complete adjuvant-induced rheumatoid arthritis and lipopolysaccharide-induced inflammatory responses.  JOURNAL OF ETHNOPHARMACOLOGY.  268,  113602

단행본

  • (2017)  Encyclopedia of signaling molecules.  Springer Science.  주저자
  • (2016)  Kaempferol: Biosynthesis, food sources and therapeutic uses.  Nova publishers.  주저자
  • (2013)  Karp 세포생물학: 새롭고 알기쉬운 세포의 구조와 기능.  (주)월드사이언스.  공동

수상/공훈

  • Associate Editor : 5 international journals